动物生物化学（全英文）特邀讲座
授课时间地点：
12月18日-12月20日
逸夫楼3044
授课老师
Jing Yang Professor,
Comparative Biosciences
University of Illinois at Urbana-Champaign
BIOGRAPHY:
Dr. Jing Yang completed his PhD in Shanghai Institute of Biochemistry, China. In 2004, he joined the faculty at the Ohio State University, Department of Pediatrics. In 2011, he moved his laboratory to the Department of Comparative Biosciences at the College of Veterinary Medicine, University of Illinois at Urbana-Champaign.
RESEARCH INTERESTS:
Vertebrate embryonic development, reversible protein phosphorylation, signaling transduction, maternal genes.
Description: This course is designed to provide an overview of different types of cells in adult human/animal and their developmental origins.
Recommended text: None
Classes will consist of lectures provided by the instructor. Students will be expected to read class materials, attend class, participate in class discussions, and give presentations on primary research papers related to the class topics.
Presentations: The students will be divided into several groups. Each group will discuss and present a selected research paper. The presentation must include background, a statement of the hypothesis, a brief description of the study design, the results, conclusions, and strengths/limitations of the study. All students are required to read the selected paper and to be prepared to discuss the paper being presented in class.
Grading policy: Grades will be based on attendance, presentations, and participation in class discussions.
I) Cells and tissues in adult
1) Structure of the cell
2) Epithelial cells
3) Common cell types in the skin
4) Organization of connective tissues
5) Muscle
6) Neurons and glia cells
7) Blood/bone marrow
8) Cartilage and bone tissues
9) Immune cells
10) Endocrine organs
II) Developmental origins cells in adult human/animal
1) History of developmental biology studies
2) Overview of vertebrate embryonic development
3) Morphological changes during gastrulation and neurulation
4) Signaling pathways essential for early embryonic development
5) Vertebrate germ layer specification
6) Specification of the primary axis
7) Somite formation and differentiation
8) Limb development
III) Student presentation
1) Shinya Yamanaka’s group, Cell. 2006, 126(4):663-76
2) Zhang X, Abreu JG, Yokota C, MacDonald BT, Singh S, Coburn KL, Cheong SM, Zhang MM, Ye QZ, Hang HC, Steen H, He X. Cell. 2012 22;149(7):1565-77
3) Clift D, McEwan WA, Labzin LI, Konieczny V, Mogessie B, James LC, Schuh M. Cell. 2017 pii: S0092-8674(17)31255-2.
4) Heasman J, Crawford A, Goldstone K, Garner-Hamrick P, Gumbiner B, McCrea P, Kintner C, Noro CY, Wylie C. Cell. 1994 Dec 2;79(5):791-803.
5) Huangfu D, Liu A, Rakeman AS, Murcia NS, Niswander L, Anderson KV. Nature. 2003 Nov 6;426(6962):83-7
6) Dosch R, Wagner DS, Mintzer KA, Runke G, Wiemelt AP, Mullins MC. Dev Cell. 2004 Jun;6(6):771-80
Wagner DS, Dosch R, Mintzer KA, Wiemelt AP, Mullins MC. Dev Cell. 2004 Jun;6(6):781-90
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