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倪迎冬

2014-9-30 17:15:29   来源:南京农业大学动物医学院   浏览:10
姓名

倪迎冬

性 别 照片 001.jpg
出生日期

1973年11月

籍 贯

江苏 淮安

毕业院校

南京农业大学

研究方向:
反刍动物消化道黏膜屏障与免疫
个人简历:

倪迎冬,女,教授/博士生导师,197311月出生,祖籍江苏淮安。现为南京农业大学“133工程优秀骨干教师2013教育部新世纪优秀人才1994-1998年就读于南京农业大学动物医学院,获农学学士学位;2003年毕业于南京农业大学动物医学院,获农学博士学位。主讲《动物生理学》和《神经内分泌生理学》2门课程。主要研究方向:反刍动物消化生理与消化道免疫。2015年在研自然科学基金面上项目2项,“SARA产生的内源性LPS对结肠黏膜上皮细胞凋亡的影响及GCs的参与(312724702013.01-2016.12微生物群感信号分子acy-HSLSARA引起的结肠黏膜上皮细胞凋亡中的作用及机制研究(315724332016.01-2019.12。教育部新世纪人才计划项目1项,饲喂高谷物精料损伤奶山羊肠黏膜屏障的机理研究(NCET-13-,教育部新世纪人才计划(2013)。已主持完成国家自然科学基金青年基金1项。作为研究骨干成员,参加国家重大基础研究计划973计划牛奶重要营养品质形成与调控机理(2011CB100800研究, 2011-2015;参加转基因生物新品种培育重大专项猪糖皮质激素受体基因组织特异性调控元件和转录因子的高通量筛选和功能鉴定、参加国家公益性行业专项畜禽福利养殖关键技术体系研究与示范、参加国家自然基金广东省联合基金广东优质黄羽肉鸡蛋白质代谢的分子机制及其调控和浙江省自然科学基金浙江优良家禽种质研究与开发利用等科研项目的研究工作。参编十二五全国规划教材1部(动物生理学); 主编十二五全国规划教材1部(动物生理学实验指导教材);制定国家标准1项(饲料添加剂7-二羟基异黄酮,GB/T25174-2010)。近5年来,共发表科研论文50余篇,其中SCI论文30篇。 2004-2006年先后两次赴德国联邦农业科学院动物科学和行为研究所进行科研合作研究。2013-2014年获得国家留学基金委青年骨干教师出国留学项目资助赴美国佛蒙特大学研修。

代表性论著:

1.    Shiyu Tao, Jing Tian, Rihua Cong, Yongqian Duanmu, Haibo Dong, Yingdong Ni*, Ruqian Zhao. Down-regulation of prostaglandin E2 (PGE2) is involved in the damages of the hindgut mucosa in lactating goats after fed a high-concentrate diet. Exp Physiol 101.2 (2016) pp 272–281.

2.      Yongqian Duanmu, Rihua Cong, Shiyu Tao, Jing Tian, Haibo Dong, Yuanshu Zhang, Yingdong Ni* and Ruqian Zhao. Comparative proteomic analysis of the effects of high-concentrate diet on the hepatic metabolism and inflammatory response in lactating dairy goats. Journal of Animal Science and Biotechnology. 2016,7:5 DOI 10.1186/s40104-016-0065-0.

3.      Shiyu Tao, Jing Tian, Rihua Cong, Lili Sun, Yongqian Duanmu, Haibo Dong, Yingdong Ni* and Ruqian Zhao. Activation of cellular apoptosis in the caecal epithelium is associated with increased oxidative reactions in lactating goats after feeding a high-concentrate diet. Exp Physiol 100.3 (2015) pp 278–287.

4.      Liu J, Duan Y, Hu Y, Sun L, Wang S, Fu W, Ni Y*, Zhao R. Exogenous administration of chronic corticosterone affects hepatic cholesterol metabolism in broiler chickens showing long or short tonic immobility. Comp Biochem Physiol A Mol Integr Physiol. 2015, 191:53-58.

5.      Tao S, Duanmu Y, Dong H, Ni Y*, Chen J, Shen X, Zhao R. High concentrate diet induced mucosal injuries by enhancing epithelial apoptosis and inflammatory response in the hindgut of goats. PLoS One. 2014 Oct 30;9(10):e111596. doi: 10.1371/journal.pone.0111596. eCollection 2014.

6.      Jia YY, Wang SQ, Ni YD*, Zhang YS, Zhuang S, Shen XZ. High concentrate-induced subacute ruminal acidosis (SARA) increases plasma acute phase proteins (APPs) and cortisol in goats. Animal. 2014 Sep;8(9):1433-8. doi: 10.1017/S1751731114001128. Epub 2014 May 22.

7.      Tao S, Duanmu Y, Dong H, Tian J, Ni Y*, Zhao R. A high-concentrate diet induced colonic epithelial barrier disruption is associated with the activating of cell apoptosis in lactating goats. BMC Vet Res. 2014 Sep 26;10(1):235.

8.      Duan Y, Fu W, Wang S, Ni Y*, Zhao R. (2014) Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens. Comp Biochem Physiol A Mol Integr Physiol. 2014 Oct;176:59-64.

9.      Fu W, Duan Y, Wang S, Ni Y*, Grossmann R, Zhao R. (2014) Comparative proteomic analysis of the breast muscle response to chronic corticosterone administration in broiler chickens showing long or short tonic immobility. Poult Sci. doi: 10.3382/ps.2013-03456.

10.  Duan Y, Fu W, Wang S, Ni Y*, Zhao R. Effects of tonic immobility (TI) and corticosterone (CORT) on energy status and protein metabolism in pectoralis major muscle of broiler chickens. Comp Biochem Physiol A Mol Integr Physiol. 169: 90-5

11.  Dong H, Wang S, Jia Y, Ni Y*, Zhang Y, Zhuang S, Shen X, Zhao R. Long-term effects of subacute ruminal acidosis (SARA) on milk quality and hepatic gene expression in lactating goats fed a high-concentrate diet. PLoS One. 2013 Dec 23;8(12):e82850. doi: 10.1371/journal.pone.0082850. eCollection 2013.

12.  Li R, Sun Q, Jia Y, Cong R, Ni Y*, Yang X, Jiang Z, Zhao R. Coordinated miRNA/mRNA expression profiles for understanding breed-specific metabolic characters of liver between Erhualian and large white pigs. PLoS One. 2012;7(6):e38716.

13.  Cong R, Jia Y, Li R, Ni Y*, Yang X, Sun Q, Parvizi N, Zhao R. Maternal low-protein diet causes epigenetic deregulation of HMGCR and CYP7α1 in the liver of weaning piglets. J Nutr Biochem. J Nutr Biochem. 2012 Dec;23(12):1647-54. doi: 10.1016/j.jnutbio.2011.11.007. Epub 2012 Mar 22.

14.  Yingdong Ni, Yanbing Huang, Yunqi Xiao, Jing Wu, Fuyu Qian, Roland Grossmann, Ruqian Zhao*. Effects of repeated injection of kisspeptin-10 on the initiation of egg-laying in juvenile quails. Anim Reprod Sci. 2012,134:203-209.

15.  Y. D. Ni*, X. J. Wei, C. X. Zhang, Y. Zhong, L. Z. Lu, R. Grossmann and R. Q. Zhao. The effect of equol injection in ovo on , , lipid metabolism and hepatic lipogenic gene expression in broilers. Animal (2012) 1.744, 6:9, 1444–1450.

16.  Y.D. Ni,*, J. Wu, H.Y. Tong, Y.B. Huang, L.Z. Lu, R. Grossmann, R.Q. Zhao. Effect of dietary daidzein supplementation on egg laying rate was associated with the change of hepatic VTG-II mRNA expression and higher antioxidant activities during the post-peak egg laying period of broiler breeders. Animal Feed Science and Technology. 2012, 177: 116–123. 10.1016/j.anifeedsci.2012.08.001.

17.  J. Wu, W. Fu, Y. Huang and Y. Ni*. Effects of Kisspeptin-10 on Lipid Metabolism in Cultured Chicken Hepatocytes. Asian-Aust. J. Anim. Sci. 2012, 9:(25): 1229-1236.

18.  Yunqi Xiao, Yingdong Ni*, Yanbing Huang, Jing Wu, Roland Grossmann, Ruqian Zhao. Effects of kisspeptin-10  on  progesterone  secretion  in  cultured  chicken  ovarian granulosa cells from preovulatory (F1–F3) follicles. Peptides, 2011, 32:2091–2097. (SCI  IF: 2.705)

19.  Li R, Hu Y, Ni Y, Xia D, Grossmann R, Zhao R. Leptin stimulates hepatic activation of thyroid hormones and promotes early posthatch growth in the chicken. Comp Biochem Physiol A Mol Integr Physiol. 2011 Oct;160(2):200-6.

20.  Wei XJ, Ni YD*, Lu LZ, Grossmann R, Zhao RQ. The effect of equol injection in ovo on posthatch growth, meat quality and antioxidation in broilers. Animal. 2011 Feb;5(2):320-7. 1.744

21.  Wei XJ, Wu J, Ni YD*, Lu LZ, Zhao RQ. Antioxidant effect of a phytoestrogen equol on cultured muscle cells of embryonic broilers. In Vitro Cell Dev Biol Anim. 2011 Dec;47(10):735-41. 1.312

22.  Li LA, Wu ZW, Yang XJ, Ni YD, Parvizi N, Zhao RQ. Effect of glucocorticoids pretreatment on steroidogenic capacity of adrenocortical cells isolated from Meishan piglets. In Vitro Cell Dev Biol Anim. 2011 Aug;47(7):425-30.

23.  Y. Ni, L. Lu, J. Chen and R. Zhao*. Changes of Hypothalamic GnRH-I, POMC and NPY mRNA Expression and Serum IGF-I and Leptin Concentrations during Maturation of Shaoxing Ducks (Anas platyrhynchos) Asian-Aust. J. Anim. Sci. 2011, 24(9) : 1211-1216.

24.  Ni YD, Hong WJ, Zhou YC, Grossmann R, Zhao RQ. Dual effects of daidzein on chicken hepatic vitellogenin II expression and estrogen receptor-mediated transactivation in vitro. Steroids. 2010 Mar;75(3):245-51.

25.  Yuan L, Ni Y, Barth S, Wang Y, Grossmann R, Zhao R. Layer and broiler chicks exhibit similar hypothalamic expression of orexigenic neuropeptides but distinct expression of genes related to energy homeostasis and obesity. Brain Res. 2009 Jun 1;1273:18-28.

26.  Ni Y, Zhu Q, Zhou Z, Grossmann R, Chen J, Zhao R. Effect of dietary daidzein on egg production, shell quality, and gene expression of ER-alpha, GH-R, and IGF-IR in shell glands of laying hens. J Agric Food Chem. 2007 Aug 22;55(17):6997-7001.

27.  Ni Y, Zhou Y, Lu L, Grossmann R, Zhao R*. (2007) Developmental changes of FSH-R, LH-R, ER-beta and GnRH-I expression in the ovary of prepubertal ducks (Anas platyrhynchos). Anim Reprod Sci. 100(3-4): 318-328.

28.  Li Y, Yuan L, Yang X, Ni Y, Xia D, Barth S, Grossmann R, Zhao RQ. Effect of early feed restriction on myofibre types and expression of growth-related genes in the gastrocnemius muscle of crossbred broiler chickens. Br J Nutr. 2007 Aug;98(2):310-9.

29.  Zhao RQ, Zhou YC, Ni YD, Lu LZ, Tao ZR, Chen WH, Chen J. Effect of daidzein on egg-laying performance in Shaoxing duck breeders during different stages of the egg production cycle. Br Poult Sci. 2005 Apr;46(2):175-81.

30.  Zhao R, Wang Y, Zhou Y, Ni Y, Lu L, Grossmann R, Chen J. Dietary daidzein influences laying performance of ducks (Anas platyrhynchos) and early post-hatch growth of their hatchlings by modulating gene expression. Comp Biochem Physiol A Mol Integr Physiol. 2004 Aug;138(4):459-66.

31.  Zhao R, Wang Y, Zhou Y, Ni Y, Lu L, Grossmann R, Chen J. Dietary daidzein influences laying performance of ducks (Anas platyrhynchos) and early post-hatch growth of their hatchlings by modulating gene expression. Comp Biochem Physiol A Mol Integr Physiol. 2004 Aug;138(4):459-66.

32.  Xu Q, Zhao Z, Ni Y, Zhao R, Chen J. Effect of recombinant growth hormone on expression of growth hormone receptor, insulin-like growth factor mRNA and serum level of leptin in growing pigs. Sci China C Life Sci. 2003 Apr;46(2):205-11.

33.  Zou H, Li R, Jia Y, Yang X, Ni Y, Cong R, Soloway PD, Zhao R. Breed-Dependent Transcriptional Regulation of 5'-Untranslated GR (NR3C1) Exon 1 mRNA Variants in the Liver of Newborn Piglets. PLoS One. 2012;7(7):e40432.

34.  贾媛媛,王绍庆,常广军,张源淑,庄苏,倪迎冬*沈向真,陈杰, 赵茹茜. 高精料诱导的SARA对泌乳期山羊皮质醇的影响。草业学报,2012,421):259-266.

35.  董海波,王绍庆,贾媛媛,倪迎冬*张源淑,沈向真,赵茹茜. 亚急性瘤胃酸中毒时山羊下丘脑食欲调节因子mRNA的表达变化。江苏农业科学,2013,14123-25.

36.  董海波,王绍庆,贾媛媛,端木永前,陶诗煜,倪迎冬* ,张源淑,庄苏,沈向真,赵茹茜长期饲喂高精料日粮对泌乳期山羊血液生化参数及组织中糖代谢相关基因表达的影响. 草业学报,2014:523),295-302.

37.  肖蕴祺,倪迎冬*, 吴晶,黄炎冰,赵茹茜。(2012) Kisspeptin-10对无血清培养鸡F1级卵泡颗粒细胞孕酮分泌的影响及机制研究。中国农业科学. 45(2): 391-398.

38.  吴晶,倪迎冬*, 肖蕴祺,黄炎冰,赵茹茜。Kisspeptin-10对鹌鹑产蛋启动及肝脏脂代谢的影响。南京农业大学学报。南京农业大学学报 201235( 3) : 89-93.

39.  钱福玉,史盈频,裴静,骆海波,黄炎冰,倪迎冬*. Kisspeptin 对蛋鹌鹑卵巢发育与内分泌的影响。畜牧与兽医,2012,1044):13-16.

40.  倪迎冬,袁丽霞,饶开晴,李玥,杨晓静,赵茹茜。早期和后期限饲对肉鸡采食量及下丘脑POMCNPY和瘦素受体mRNA转录的影响。南京农业大学学报。2011,343):112-116.

41.  吴晶,魏晓静,管少华,裴彬,倪迎冬*。蛋内注射雌马酚对肉鸡性腺发育的影响。畜牧与兽医,20101142):72-74.

42.  倪迎冬, 吕锦芳, 饶开晴, 李玥, 马昕源, 王晋, 陈杰, 赵茹茜。性成熟启动时间不同的母鸡Leptin及其受体mRNA表达的差异. 南京农业大学学报, 2008, 31(1): 153-157.

科研项目:
  • Kisspeptin/GPR54信号系统在鸭生殖启动中的作用研究,国家自然科学基金项目(30800809),主持。
  • 主持国家自然科学基金面上项目:SARA产生的内源性LPS对结肠黏膜上皮细胞凋亡的影响及GCs的参与(312724702013.01-2016.12
  • 主持国家自然科学基金面上项目: “微生物群感信号分子acy-HSLSARA引起的结肠黏膜上皮细胞凋亡中的作用及机制研究(315724332016.01-2019.12
  • 主持教育部新世纪人才计划项目:饲喂高谷物精料损伤奶山羊肠黏膜屏障的机理研究(NCET-13-”。
  • 参加国家重大基础研究计划973计划牛奶重要营养品质形成与调控机理(2011CB100800研究, 2011-2015  (骨干成员)。
  • 参加国家公益性行业专项畜禽福利养殖关键技术体系研究与示范”(骨干成员)(2011-2015)。
  • 参加农业部转基因专项:猪糖皮质激素受体基因组织特异性调控元件和转录因子的高通量筛选和功能鉴定,转基因生物新品种培育重大专项(2009ZX08009-138B),子课题负责人。
  • 荣誉及奖项:

    1. 教育部新世纪人才(2013)

    2. 获武汉回盛奖教金(2014年)

    3.年度考核优秀(2012、2014)

    联系方式:
    niyingdong@njau.edu.cn
     
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